Assembly of Productive T Cell Receptor δ Variable Region Genes Exhibits Allelic Inclusion
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چکیده
منابع مشابه
Assembly of Productive T Cell Receptor δ Variable Region Genes Exhibits Allelic Inclusion
The generation of a productive "in-frame" T cell receptor beta (TCR beta), immunoglobulin (Ig) heavy (H) or Ig light (L) chain variable region gene can result in the cessation of rearrangement of the alternate allele, a process referred to as allelic exclusion. This process ensures that most alphabeta T cells express a single TCR beta chain and most B cells express single IgH and IgL chains. As...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1998
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.188.8.1465